In the field of biochemistry, polypeptide synthesis is a key technique that is widely applied in drug research and development, biotechnology research, and clinical treatment. Nutsche filter reactor, as an important equipment for polypeptide synthesis, is designed to allow modular connection with other equipment, facilitating expansion and meeting the constantly changing demands of polypeptide synthesis. Its unique application brings a more convenient and efficient effect to polypeptide synthesis.

During the process of polypeptide synthesis, Nutsche filter reactor plays a core role. It can be connected with various equipment such as activation kettles, cleavage kettles, concentration kettles, and precipitation kettles to form a complete polypeptide synthesis production line.

 Firstly, in the activation kettle, amino acids are activated and prepared for reaction with amino acid residues on the solid phase carrier. Subsequently, the activated amino acids are transferred to Nutsche filter reactor to undergo condensation reaction with amino acid residues on the carrier to form peptide bonds. This step is crucial in polypeptide synthesis. Nutsche filter reactor provides a stable reaction environment and precise control of temperature and pH to ensure the smooth progress of the reaction.

Next, the cleavage kettle is used to cleave the synthesized polypeptide from the solid phase carrier to obtain the free polypeptide. The concentration kettle is used to concentrate the polypeptide solution after cleavage to increase the polypeptide concentration. Finally, the precipitation reactor is used to remove impurities from the concentrated polypeptide solution to obtain the high-purity target polypeptide.

Through connection with equipment such as activation reactor, cleavage reactor, concentration reactor, and precipitation reactor, Nutsche filter reactor realizes the automation and continuity of polypeptide synthesis, greatly improving the synthesis efficiency. This connection method not only enhances the synthesis efficiency but also ensures the purity and quality of the polypeptide product. Its advantages of high efficiency, high purity, flexibility, scalability, and environmental friendliness provide strong support for the development of the polypeptide synthesis field. With the continuous advancement of technology and in-depth application, Nutsche filter reactor will continue to promote innovation and development in polypeptide synthesis processes in the future.